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Exam Code: C1000-083 Foundations of IBM Cloud V2 mission January 2024 by Killexams.com team

C1000-083 Foundations of IBM Cloud V2

Test Detail:
The IBM C1000-083 exam, Foundations of IBM Cloud V2, is designed to assess the knowledge and skills of individuals in foundational concepts related to IBM Cloud. The exam tests the candidate's understanding of cloud computing principles, IBM Cloud offerings, and the ability to apply IBM Cloud solutions to real-world scenarios.

Course Outline:
The Foundations of IBM Cloud V2 course provides comprehensive training on the fundamental concepts of cloud computing and IBM Cloud solutions. The course covers various topics, including cloud architecture, cloud deployment models, cloud services, and the use of IBM Cloud services for building and deploying applications. The following is a general outline of the key topics covered:

1. Cloud Computing Concepts:
- Introduction to cloud computing and its benefits.
- Cloud deployment models: public, private, hybrid, and multi-cloud.
- Cloud service models: IaaS, PaaS, and SaaS.
- Cloud security and compliance considerations.

2. Introduction to IBM Cloud:
- Overview of IBM Cloud offerings and services.
- IBM Cloud architecture and infrastructure components.
- IBM Cloud deployment models and options.
- IBM Cloud pricing and billing models.

3. IBM Cloud Services:
- IBM Cloud compute services: virtual servers, containers, and serverless computing.
- IBM Cloud storage services: object storage, block storage, and file storage.
- IBM Cloud networking services: virtual private networks, load balancers, and DNS.
- IBM Cloud database services: SQL and NoSQL databases.

4. Application Development on IBM Cloud:
- IBM Cloud development tools and environments.
- Building and deploying applications on IBM Cloud.
- Integration with IBM Watson services for AI and machine learning.

Exam Objectives:
The C1000-083 exam assesses the candidate's knowledge and skills in the following areas:

1. Cloud Computing Concepts:
- Understanding of cloud computing principles, deployment models, and service models.
- Knowledge of cloud security and compliance considerations.

2. IBM Cloud Fundamentals:
- Familiarity with IBM Cloud offerings, architecture, and infrastructure components.
- Understanding of IBM Cloud deployment models and pricing models.

3. IBM Cloud Services:
- Knowledge of IBM Cloud compute, storage, networking, and database services.
- Ability to differentiate between different IBM Cloud service offerings.

4. Application Development on IBM Cloud:
- Understanding of IBM Cloud development tools and environments.
- Knowledge of building and deploying applications on IBM Cloud.
- Awareness of integration possibilities with IBM Watson services.

Syllabus:
The C1000-083 course syllabus provides a detailed breakdown of the topics covered in the training program. It includes specific learning objectives, hands-on exercises, and case studies to enhance the candidate's understanding and application of IBM Cloud concepts. The syllabus may cover the following areas:

- Cloud Computing Concepts and Models
- Introduction to IBM Cloud
- IBM Cloud Compute Services
- IBM Cloud Storage Services
- IBM Cloud Networking Services
- IBM Cloud Database Services
- Application Development on IBM Cloud
Foundations of IBM Cloud V2
IBM Foundations mission

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C1000-083
Foundations of IBM Cloud V2
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Question: 53
Which statement describes the Watson Assistant service on IBM Cloud?
A. IBMs AI engine targeted at the consumer smart home device market
B. IBMs AI product that allows for building, training, and deploying conversational interactions into any application,
device, or channel
C. A trained virtual agent with skills that address conversational interactions across all domains
D. IBMs API product designed to facilitate the creation of complex machine learning algorithms through a graphical
interface
Answer: B
Reference:
https://www.ibm.com/in-en/cloud/watson-
assistant#:~:text=Watson%20Assistant%20is%20IBM%27s%20AI,any%20application%2C%20device%20or
%20channel
.
Question: 54
What tool should be used to transmit encrypted traffic between two VPCs in IBM Cloud that are each in a different region?
A. Secure Gateway for VPC
B. Firewall1 for VPC
C. VPN for VPC
D. Hyper Protect for VPC
Answer: C
Reference:
https://cloud.ibm.com/docs/vpc?topic=vpc-using-vpn
Question: 55
Which IBM Cloud offering brings IBM zLinux capabilities into the cloud?
A. VMware vCenter Server
B. Bare Metal Server
C. Hyper Protect Virtual Server
D. Power Systems Virtual Server
Answer: C
Reference:
https://www.ibm.com/blogs/systems/the-best-of-ibm-z-and-linuxone-in-the-public-and-private-cloud/
Question: 56
How long do Lite accounts remain open before expiring?
A. They never expire
B. 365 days
C. 180 days
D. 30 days
Answer: D
Reference:
https://cloud.ibm.com/docs/account?topic=account-
accounts#:~:text=You%20can%20wake%20up%20your,with%20Lite%20plans%20are%20deleted
.
Question: 57
What is the IBM Cloud Hyper Protect DBaaS for MongoDB?
A. A LinuxONE-powered cloud database solution for enterprise workloads with sensitive data
B. A LinuxOne-powered on premises database solution for enterprise workloads with default data
C. A LinuxONE-powered on premises database solution for enterprise workloads with sensitive data
D. A LinuxOne-powered cloud database solution for enterprise workloads with default data
Answer: A
Reference:
https://www.ibm.com/cloud/hyper-protect-dbaas
Question: 58
Which IBM Cloud for VMware Solutions add-on service provides load balancing and traffic management services at a local and global
scale?
A. HyTrust CloudControl
B. HCX
C. FortiGate Security Appliance
D. F5 BIG-IP
Answer: D
Reference:
https://cloud.ibm.com/docs/vmwaresolutions?topic=vmwaresolutions-getting-started
Question: 59
Which IBM Garage Method for Cloud practice leverages Enterprise Design Thinking?
A. Envision
B. Culture
C. Learn
D. Reason
Answer: B
Reference:
https://www.ibm.com/garage/method/
Question: 60
Which VPC component would have a Front End Listener and Back End Pool?
A. A Floating IP
B. An Access Control List
C. A Public Gateway
D. A Load Balancer
Answer: D
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IBM Foundations mission - BingNews https://killexams.com/pass4sure/exam-detail/C1000-083 Search results IBM Foundations mission - BingNews https://killexams.com/pass4sure/exam-detail/C1000-083 https://killexams.com/exam_list/IBM IBM Eyes SMBs With 'Foundations' Servers

server

Lotus unveiled the new initiatives at its annual Lotusphere conference in Orlando where it also announced a development effort with SAP to link that company's business applications with Notes, new "mashup" development tools, and details of upcoming releases of Notes/Domino, Symphony, Quickr and Connections.

"Historically, it's been hard for small companies to take advantage of what IBM has to offer," Lotus general manager Mike Rhodin said during his keynote speech. At a press conference later he said Foundations and the new software-as-a-service offerings, being developed under the code name "Bluehouse," are "a major expansion of our strategy in to SMB."

The Foundations servers will be sold primarily through Lotus channel partners targeting SMB customers with between five and 500 customers and will compete head-to-head with Microsoft Small Business Server. The servers are based on Lotus software and server packages from Toronto-based Net Integration Technologies (Nitix) that IBM announced last week that it is in the process of acquiring for an undisclosed sum.

Taking a cue from Apple CEO Steve Jobs, who debuted Apple's new ultra-thin "Air" Macintosh at last week's MacWorld show by pulling it from an interoffice envelope, Rhodin did the same onstage at Lotusphere, pulling a Foundations server from an only slightly bulkier package.

The first Foundations server, due to ship later this year, will offer a range of collaboration tools and other software including e-mail, file management, directory services, fire wall, backup and recovery, and office productivity software. Lotus executives briefed channel partners attending Lotusphere about the new product on Sunday.

A Foundations communications server is also in the works with others to follow, some incorporating software from ISV partners, Rhodin said.

The Bluehouse software-as-a-service offerings will provide on-demand collaboration tools for SMBs, such as the ability to share files, initiate online meetings and manage contacts. Rhodin said the first contact-management software-as-a-service app is now available on a beta test basis.

Lotus also expects to offer the Bluehouse services through its channel partners, but Rhodin said the company is still working out the details, such as pricing and sales practices, given that the whole software-as-a-service business model is still evolving.

IBM is in the midst of a broad effort to restructure its sales operations and channel programs to regain momentum in worldwide SMB IT markets that are expected to total $550 billion this year.

Rhodin said Foundations and Bluehouse are components of that effort. "This is clearly an extension of the strategies IBM has been announcing over the course of the last few weeks," he said during the press conference."

Sunday Robert Wong, Lotus director of worldwide SMB, channels and software-as-a-service sales, told business partners Sunday that sales of IBM Lotus products through the channel are growing faster than direct sales and the executive urged resellers to take advantage of that momentum.

"With the [product] portfolio we have right now, plus the announcement of Foundations, you have probably one of the richest portfolios in decades," Wong said. He exhorted channel partners to expand their sales efforts beyond Lotus Notes/Domino and sell them other Lotus software such as the Sametime instant messaging/web conferencing software and Quickr collaboration application. "You need to move out of your comfort zone," he said. "Learn to link value across the product portfolio."

IBM Lotus is also seeing growing interest from SMBs in software-as-a-service offerings, Wong said. He pitched channel partners on providing hosted versions of Lotus products arguing that they provide a recurring revenue stream that is more profitable over the long term than installing on-premise applications.

This article has been updated

Sun, 10 Dec 2023 22:35:00 -0600 text/html https://www.crn.com/news/applications-os/205905196/ibm-eyes-smbs-with-foundations-servers
IBM Expands Foundation Appliance Line, Adds Virtualization Through VMware Deal

virtualization

IBM also said a new addition to the Lotus Foundations line, Lotus Foundations Start, will be based on the vendor's own x86-based System x server. Until now Lotus Foundations servers have been based on server technology developed by Toronto-based Net Integration Technologies Inc. (Nitix) which IBM acquired earlier this year.

IBM sells the Lotus Foundations appliances exclusively through the channel. Targeting small and mid-size businesses, the plug-and-play appliances, which support up to 500 users, are designed to be easy to maintain and administer. The systems can be installed in as little as one hour, said Caleb Barlow, integration executive for Nitix/Lotus Foundations.

Lotus Foundations competes head-to-head with Microsoft's Windows Small Business Server and Windows Essential Business Server. This week Microsoft is slated to begin shipping the new Windows Essential Business Server 2008, a pre-configured software bundle targeting mid-size companies with up to 250 PCs. It's also expected to begin shipping Windows Small Business Server 2008, a new release of the popular package for small businesses.

Lotus Foundations Start, slated for availability next month, is pre-configured with Notes/Domino collaboration software; Lotus Symphony document, spreadsheet and presentation applications and anti-virus/anti-spam applications. The servers also offer a simplified backup and restore capability.

Under the deal with VMware, IBM is adding the VMware hypervisor to the Lotus Foundations server, allowing customers to run Windows and Windows applications on the system. VMware for the Lotus Foundations servers is currently in beta testing. The Lotus Foundations servers run on an optimized version of Novell's SUSE Linux Enterprise Server 10 with an operating system kernel that's less than 100 Mbytes, according to Barlow. The kernel is stored on a chip, so the server will continue to run even if the system's disk crashes, he said.

OnSite Technology, a Jacksonville, Fla.-based solution provider for small businesses, has sold the Foundations servers for several years. "They're just so reliable. It's just an all-around perfect thing for a small business," said OnSite owner Rick Kane. He encourages customers to adopt Foundations "to get away from Windows and the bloatware that goes with it."

He said he would beta test the VMware for Foundations, although he was skeptical whether it would be a big seller among small businesses.

On Nov. 21, IBM will ship the IBM Smart Business Developers' Kit ISVs can use to package their existing Domino applications for Lotus Foundations appliances.

Barlow said Foundations offers channel partners the opportunity to build fixed-price services around the server, including remote management services. "This enables a different business model." IBM is also providing partners with free support for Foundations, he said.

The Lotus Foundations server software is priced at $849 for five users. Pricing for the new server hardware has not been disclosed; The current server hardware is priced at $2,499.

Sun, 10 Dec 2023 22:35:00 -0600 text/html https://www.crn.com/news/applications-os/212001496/ibm-expands-foundation-appliance-line-adds-virtualization-through-vmware-deal
Embracing AI and cyber resiliency: IBM enhances its portfolio as storage moves into the enterprise spotlight

Speeds and feeds in the storage market are so 2020. Now the conversation is all about data security and how storage can enable artificial intelligence to drive business results.

This was one of the key messages that emerged from two major events hosted by theCUBE, SiliconANGLE Media’s livestreaming studio, and IBM Corp. in July and October. Executives from IBM, company partners and industry experts appeared on the programs to share their insights into how the world of storage has undergone its own transformation.

“Although storage has presented itself mainly as a background service, it’s becoming more and more forefront in the consideration for what an appropriate data strategy needs to look like,” said Scott Baker, chief marketing officer and vice president of IBM Infrastructure Portfolio product marketing at IBM. “The future of storage is expected to be characterized by the extensive use of AI to unlock data value and provide a solid foundation for businesses to anticipate and withstand market shifts.”

Baker spoke to theCUBE in July during the IBM Storage Summit, an exclusive broadcast on theCUBE that focused on new capabilities for data and AI. In October, theCUBE offered a second exclusive broadcast, “Beyond Firewalls: Resilience Strategies for All,” that featured interviews with IBM executives and partners to discuss how storage now plays an important role in strengthening cyber resilience against data attacks. (* Disclosure below.)

Shifting workloads for the right data, in the right place

The influence of AI in storage gained significant momentum in 2023 as organizations pursued uses for the technology in several operational areas. IBM noticed a shift in workloads among its customers that required a different approach to the challenge of scale and management of data flows through the information supply chain.

“We’ve started to see changes in workloads from media and entertainment, healthcare, life sciences [and] financial services sectors,” said Christopher Maestas, worldwide executive solutions architect at IBM, in an interview during the Storage Summit in July. “AI really has changed it, because it picked the middle of the road — not the itty-bitty files that you see or the large streaming data that you’ve been doing. We’re really seeing that data size change and, again, having to adapt to a different data size that we’ve not traditionally handled in the past.”

To accommodate shifting changes in data size driven by AI, IBM launched several new initiatives for its storage portfolio. These included introduction of the IBM Storage Scale 6000, scale-out storage for file and object that’s targeted at unstructured data and AI and machine learning workloads.

The enhancements to IBM’s Storage Scale platform highlighted the company’s focus on compression, an ability to shrink the size of stored data. Compression can maximize storage capacity, improve the speed of file transfers and lower overall costs. Updates to Storage Scale System 6000 included inline hardware accelerated data compression using 38TB Flash Core Modular drives.

“Compression is a huge concept in storage, said Sarbjeet Johal, guest analyst, during a panel discussion on theCUBE’s broadcast in July. “How much you can compress and where we are storing it, that also matters. We still have a long way to go to bring intelligence into storage, because we are storing a lot more data.”

IBM also enhanced its Storage Fusion offering, a data services solution that integrates compute, storage and networking into a hyperconverged system. The objective was to eliminate frustration among data scientists who were bogged down by endless searches for the right information, according to Pete Brey, global product executive, IBM Storage Fusion.

“We have unique capabilities in terms of being able to catalog and label and tag the data so it’s quickly and easily found,” said Brey, during an interview on theCUBE. “The number one problem for the data scientists today is not how long my inferencing takes or not how long it takes to do model training; can I get to the right data quickly? Some of the estimates are like 80% to 90% of their time is spent just trying to find the right data, and that’s the problem that we solve.”

IBM’s work with Storage Fusion also offers insight into its integration with the cloud-native world and Red Hat Inc. A combination of Storage Fusion with Red Hat OpenShift has created a comprehensive platform that can support both Kubernetes applications and virtual machines.

“We work very closely with our friends at Red Hat … they have a technology called OpenShift Virtualization based on KubeVirt,” Brey noted. “Customers bringing these VMs over want to be able to co-host not just the containers, but also the VMs together and have a single substrate to support it all. That’s really what Fusion is all about.”

Rising data breach costs

IBM’s storage architecture has also been designed with cybersecurity in mind, an important element given the speed and preponderance of attacks plaguing businesses today. While IBM built elements into its FlashCore Modules that can detect threats, adoption of AI has complicated the picture for security operations teams.

“Just like we have access to AI to help with detection, the bad guys have access to the same AI to help cause attacks faster,” said Ram Parasuraman, executive director of IBM, during an interview with theCUBE in October. “It’s about how you use and harness the tools. There’s research from IBM that states what used to take attackers 60 days to cause these attacks today take less than four days.”

Part of IBM’s message is that cyber vulnerability comes at a cost. The company’s annual “Cost of a Data Breach” study pegged the average financial hit from a breach globally at approximately $4.5 million per incident. This is where AI could make a significant difference, according to Jeff Crume, distinguished engineer, cybersecurity architect and chief technology officer of IBM Security Americas, in his appearance on theCUBE in October.

“One thing that came from that report is that the most significant way to cut the cost of a data breach was organizations who had an extensive use of AI and automation,” Crume said. “They saved on average $1.76 million off that $4.5 million. That was the most significant way to cut the cost of that data breach.”

While IBM’s customers have invested in perimeter defenses, many of them have also turned to the company for guidance in data resilience, driven by the harsh reality that breaches have become inevitable. IBM’s executives noted throughout their discussions on theCUBE that the process for protection is a journey to be followed one step at a time.

“You can take baby steps — cybersecurity [and] data resilience is not about an on/off switch,” said Del Hoobler, principal storage software advanced technology specialist at IBM, during the broadcast event in October. “It’s a spectrum, from very weak to very strong. You never can be perfectly data resilient. The most important thing is to get started.”

(* Disclosure: TheCUBE is a paid media partner for the IBM Storage Summit and the “Beyond Firewalls: Resilience Strategies for All” event. Neither IBM Corp., the sponsor of theCUBE’s event coverage, nor other sponsors have editorial control over content on theCUBE or SiliconANGLE.)

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Fri, 29 Dec 2023 01:45:00 -0600 en-US text/html https://siliconangle.com/2023/12/29/embracing-ai-and-cyber-resiliency-ibm-enhances-its-portfolio-as-storage-moves-into-the-enterprise-spotlight-beyondfirewalls/
Is Our Critical Infrastructure Ready For AI?

From individuals using ChatGPT for fun or function to enterprises applying artificial intelligence (AI) to automate tasks, the use of AI tools has exploded over the last few years. AI tools are becoming commonplace in today’s business.

According to IBM, 43% of CEOs are using AI to inform strategic decisions, and 75% of CEOs believe having the most advanced generative AI is the key to success.

The possibilities offered by AI are staggering, with almost limitless global potential. But to achieve that promise, operators of critical enterprise and government infrastructure, like transit systems, hospitals, and financial institutions, need to start with the right technology foundation.

The limitless potential of AI

Commercialization of AI has made massive leaps forward in recent years and 2024 stands to mark another year of advancement. At the same time, innovations in quantum computing and digital twins for industrial environments are closely coupled with applications of AI. Together, these technologies are poised to help industries achieve unprecedented levels of productivity. AI alone is expected to support the creation of 97 million jobs by 2025 and contribute upwards of $4.4 trillion to the world economy every year. Goldman Sachs estimates that AI could raise the global GDP by 7% over the next decade.

Many of these gains will come from increased efficiency through the mainstream application of predictive analytics and other operational optimizations. It is claimed that AI could augment or automate up to 70% of work tasks. That could boost overall productivity by up to 3.3% and give workers time to focus on higher-value, more strategic growth tasks. But it’s not all about automation. AI can also support critical thinking and problem-solving, offering value to nearly every industry.

All of these capabilities help businesses do more with less, which is critical in the face of an aging workforce.

AI needs a strong technical foundation

As exciting as the potential of AI is, enterprises and governments need to consider what’s required to maximize the benefits, and start taking steps now to put those critical foundations in place.

Data is at the heart of AI. Processing massive lakes of relevant data requires significant compute resources. As the use of AI expands, so do the data lakes demanding more and more computing power across distributed (edge) and central locations, and relying on routing, transport, and data center infrastructures and architectures that can perform flawlessly and efficiently.

As my colleague Hardik Gohil explained in a recent interview, this often involves multiple Data Processing Units (DPUs), Central Processing Units (CPUs), and Graphics Processing Units (GPUs) all working together to process data and transfer it across workflows and between sites. Transferring data alone accounts for 25% of processing time. That means “networks must be efficient, lossless and have higher capacity because any bottleneck in a sub-optimal network would lead to a substantial impact on job completion time.” The bottom line is... your AI objectives may not be met otherwise.

Key elements of AI infrastructure that need to be in place to support your business applications integrated with AI in the future include:

  • Computational power and accelerators – Massive amounts of data gathered from your operations (IoT data, performance data, and more) coupled and interpreted to make intelligent AI decisions require massive computing power.
  • Scalable data storage and management – Data systems and storage must be able to expand rapidly as data demands grow and as data is harvested for decision-making.
  • Cloud computing platforms – These systems offer access to virtually limitless data resources for training AI models, analyzing huge data sets, and extracting actionable insights.
  • Fast, reliable network infrastructure, especially for cloud services – Cloud services depend on the ability to move data quickly, securely, and reliably. Modernized routing and optical transport networks deliver the capacity and performance needed to support the AI era.
  • Data security and integrity systems, including robust protocols and governance frameworks – With more data in use and transit, it’s more important than ever to keep it safe and look to quantum-safe security to help future-proof data integrity.
  • APIs and integration with existing systems – Introducing AI doesn’t mean replacing every system and component, so interoperability and compatibility with existing systems is a must.
  • Monitoring and automation tools for system maintenance – As system complexity grows, it’s vital to automate monitoring and issues handling to ensure everything is running at the right performance levels.
  • Compliance – Companies must ensure they remain fully in compliance with laws and regulations governing IT systems, data handling, and more.
  • Scalability – Systems must be flexible to accommodate continuously growing and shifting application, bandwidth and performance requirements.
  • Expertise and training – Continually evolving technology requires ongoing upskilling and reskilling. Choosing trusted partners and experts who are knowledgeable on AI, your operations and their unique challenges, as well as the foundational technology elements can accelerate your AI journey.

What well-implemented AI could look like

Enterprises and governments will need to make necessary investments to build the right foundations. With those elements in place, AI can help make our businesses and communities more productive and efficient.

Power utilities can integrate AI into their operational systems that intelligently shift electricity resources to better meet demand and detect anomalies in the grid before they become outages. AI tools can help better predict potential service-effecting scenarios to proactively avoid or minimize service disruptions. AI-enabled systems also can optimize the grid for maximum efficiency and sustainability.

In the finance and banking sectors, AI-enabled operations can improve transaction security, deliver advanced fraud protection, enhance analytics and forecasting, upgrade customer service, and boost regulatory compliance.

The healthcare industry is responsible for about 30% of the data generated worldwide, creating an opportunity to use AI to improve patient care, advance medical research, and optimize operations for efficiency, all while preserving the security of patient data.

Transportation operations like railways, aviation and logistics companies can use AI to make more accurate weather predictions so they can plan accordingly, improve capacity planning, and optimize routing to get people and goods to where they need to be faster and more efficiently.

Governments and first response teams can use AI paired with advanced sensing technologies to better predict and handle climate change impacts like forest fires, floods and other natural disasters. With training augmented by AI and industrial metaverse simulations, as well as enhanced situational awareness tools, agencies can respond more effectively and save more lives.

It’s time to build the foundations

The usefulness of AI depends on speed, capacity and intelligence to process mass amounts of data from various sources and meet substantial real-time data transfer requirements. It will take network infrastructure that’s resilient and robust and provides fast, low-latency connectivity, along with cloud systems that are automated, open and flexible. Indeed, each of these business-critical, mission-critical and society-critical outcomes are heavily network-dependent, and rely on a robust, performant and secure underlying network infrastructure that includes data centers as well as the routers and optical transmission equipment that seamlessly interconnects them.

With these foundations in place, AI can live up to its limitless potential, improving operations and productivity exponentially. It can enhance business operations, deliver the optimized augmented work environments we envision, and help us solve some of society’s most difficult challenges. The potential is clear, and now is the time to modernize the network infrastructure that will accelerate the future.

Wed, 03 Jan 2024 03:50:00 -0600 Houman Modarres en text/html https://www.forbes.com/sites/nokia-industry-40/2024/01/03/is-our-critical-infrastructure-ready-for-ai/
IBM sells massive campus near Research Triangle Park. New owner sees mixed-use potential. No result found, try new keyword!IBM has sold a four-building office complex near Research Triangle Park to the real estate firm that built the mixed-use projects Fenton In Cary and Durham’s Market District at American Tobacco. On ... Mon, 18 Dec 2023 07:05:00 -0600 en-us text/html https://www.msn.com/ Boehringer Ingelheim, IBM collaborate to advance generative AI and foundation models for therapeutic antibody development

Boehringer Ingelheim and IBM announced an agreement that will enable Boehringer to use IBM’s foundation model technologies to discover novel candidate antibodies for the development of efficient therapeutics.

“We are very excited to collaborate with the research team at IBM, who share our vision of making in silico biologic drug discovery a reality,” said Andrew Nixon, global head of biotherapeutics discovery at Boehringer Ingelheim. “I am confident that by joining forces with IBM scientists we will develop an unprecedented platform for accelerated antibody discovery which will enable Boehringer to develop and deliver new treatments for patients with high unmet need.”

Boehringer will be using an IBM-developed, pre-trained AI model that will be further fine-tuned on additional Boehringer proprietary data. “IBM has been at the forefront of creating generative AI models that extend AI’s impact beyond the domain of language” said Alessandro Curioni, vice president accelerated discovery, IBM Research. “We are thrilled to now bring IBM’s multimodal foundation model technologies to Boehringer, a leader in the development and manufacturing of antibody-based therapies, to help accelerate the pace at which Boehringer can create new therapeutics.”

Therapeutic antibodies are central in the treatment of many diseases, including cancer, autoimmune and infectious diseases. Despite major technological advances, the discovery and development of therapeutic antibodies covering diverse epitopes remains a highly complex and time-consuming process.

Together, Boehringer and IBM researchers will aim to accelerate the antibody discovery process through in-silico methods.  The sequence, structure and molecular profile information of disease-relevant targets as well as success criteria for therapeutically relevant antibody molecules, like affinity, specificity and developability will form the basis for the in-silico generation of new human antibody sequences. These methods rely on new IBM foundation model technologies, designed to increase the speed and efficiency of antibody discovery and quality of predicted antibody candidates.

IBM’s foundation model technologies, which have demonstrated success in generating biologics and small molecules with relevant target affinities, are used to design antibody candidates for the defined targets which are subsequently screened with AI-enhanced simulation to select and refine the best binders for the target. In a validation step, Boehringer Ingelheim will produce in mini-scales and experimentally assess the antibody candidates. Moving forward, the results from the laboratory experiments will be used to improve the in-silico methods via feedback loops.

By collaborating with leading academic and industry partners, Boehringer is building a leading digital ecosystem to enable the acceleration of drug discovery and development and create new breakthrough opportunities to transform patients’ lives.

This work also serves as the latest in IBM’s efforts to use generative AI and foundation models to accelerate discovery and creation of new biologics and small molecules. Earlier this year, the company’s generative AI model efficiently predicted physico-chemical properties of drug-like small molecules.  

The IBM biomedical foundation model technologies rely on a wide range of heterogenous, publicly available data sets, including protein-protein interactions and drug-target interactions to develop pre-trained models.  The pre-trained models are then fine-tuned on specific proprietary data of IBM’s partner to offer newly designed proteins and small molecules with the desired properties.

Boehringer Ingelheim is working on breakthrough therapies that transform lives, today and for generations to come. As a leading research-driven biopharmaceutical company, the company creates value through innovation in areas of high unmet medical need.

IBM is a leading provider of global hybrid cloud and AI, and consulting expertise. We help clients in more than 175 countries capitalize on insights from their data, streamline business processes, reduce costs and gain the competitive edge in their industries.

Wed, 29 Nov 2023 21:00:00 -0600 text/html http://www.pharmabiz.com/ArticleDetails.aspx?aid=164847&sid=2
11 Leadership Skills To Build In 2024 For Executives And Emerging Leaders

In 2024, leaders face a work landscape that has been transformed by generational diversity, complex hybrid work structures, and a rapid infusion of technology. To be a successful leader today – a modern, authentic, human leader – you must amplify a unique set of skills to meet this vastly changed environment. This is a combination of traditional leadership skills with an emphasis on soft skills (also called social skills). Here are 11 critical competencies you need to demonstrate so you can build your personal brand as a relevant and accomplished leader:

1. Emotional Intelligence (EQ)

The ability to understand and manage your own emotions, as well as recognize and influence the emotions of others, is vital for leading effectively and empathetically. At the core of this skill is self-awareness. Being self-aware is the first step in Daniel Goleman’s emotional intelligence model, and it’s the foundation for being able to build meaningful relationships with stakeholders.

2. Adaptability

The modern lexicon of the workplace includes words like 'change,' 'pivot,' and 'evolve.' Leaders must demonstrate flexibility, being able to swiftly adjust strategies and actions in response to technological shifts, worker preferences and market demands.

3. Inclusivity

Embracing and leveraging diversity, fostering an inclusive environment where all team members can thrive, is a non-negotiable leadership skill. Belonging is the key element here. When you cultivate a culture of belonging, your people do their best work in support of your mission.

4. Communication

Leaders must be storytellers, articulating visions and strategies with clarity and authenticity. Specializing in video communication for both synchronous and asynchronous interactions is vital in a hybrid work era, where in-person exchanges are less frequent. That means delivering compelling communications, while leveraging tech–messaging software and virtual meeting platforms.

5. Creative Problem-Solving

The ability to approach challenges from fresh angles and spark innovation is invaluable. Creativity is the foundation of innovation, offering potential solutions to vexing challenges.

6. Collaboration

Building and sustaining a collaborative team in a remote or hybrid setting demands skills beyond the traditional. Leaders must inspire, engage, and leverage technology to integrate collaboration into how the team works. Building team cohesion and connection is the key to engaging today’s workforce.

7. Resilience

We all learned from our experience with Covid that unexpected challenges can hijack well thought out plans. The capacity to recover quickly from difficulties, adapt to adversity, and continue to move forward is key to leadership longevity and success.

8. Strategic Thinking

Leaders have always been creators and stewards of strategy. They must be able to see the big picture, anticipate future trends and challenges, and plan accordingly. That requires an interest in what’s happening and a desire to learn and grow.

9. Learning

The only way to remain relevant in an ever-evolving environment is by being a lifelong learner. Leaders need to engage regularly in learning and become the model for team members, encouraging them to grow knowledge and skills.

10. Sustainability and Social Responsibility

Leaders must grasp the broader impact of their decisions and advocate for practices that ensure environmental care and social good. This helps them build organizations that are principled and appreciated by today’s workforce. It also helps them deliver greater profits. “72% of executives surveyed see ESG as an enabler rather than cost center,” according to a study from IBM.

11. Digital Literacy

Technology is accelerating into the workplace with the speed and precision of a NASCAR vehicle making a pit stop. Leaders need not be tech experts but must be tech-literate. They must adopt a digital mindset. “The digital mindset is a set of attitudes and behaviors that enable people and organizations to see new possibilities and chart a path for the future,” according to Paul Leonardi and Tsedal Neeley, authors of The Digital Mindset.

These skills form the mosaic of modern leadership. Mastering them does not merely equip leaders to survive in today's work environment but to thrive, driving their organizations towards success and innovation in 2024 and beyond.

William Arruda is a keynote speaker, co-founder of CareerBlast.TV and creator of the 360Reach Personal Brand Survey that helps you get candid, meaningful feedback from people who know you.

Tue, 02 Jan 2024 02:59:00 -0600 William Arruda en text/html https://www.forbes.com/sites/williamarruda/2024/01/02/11-leadership-skills-to-build-in-2024-for-executives-and-emerging-leaders/
Impact Podcast with John Shegerian Features Marti Skold-Jordan of Tractor Supply No result found, try new keyword!Jordan, Manager of the Tractor Supply Foundation & Community Relations for Tractor Supply, is a featured guest this week on the Impact ... Thu, 04 Jan 2024 18:48:00 -0600 https://www.businesswire.com/news/home/20240104265930/en/Impact-Podcast-with-John-Shegerian-Features-Marti-Skold-Jordan-of-Tractor-Supply OIN, IBM, Microsoft and the Linux Foundation team up against open-source patent trolls

The Open Invention Network (OIN) is strengthening its fight against patent trolls. The organization has announced it is partnering up with IBM, Microsoft and the Linux Foundation to protect open-source software from Patent Assertion Entities (PAEs), or patent trolls.

The OIN was created to provide patent non-aggression cross-license in the “Linux System.”

“Open source development continues to expand into new products and markets, delivering unrivaled innovation,” said Keith Bergelt, CEO of OIN. “Its use continues to spread, and patent trolls increasingly look to leverage questionable patents against open source. Our mandate is to educate business leaders about the benefits of open source and shared innovation while providing a ‘patent no-fly zone’ for Linux and adjacent open source technologies. Teaming with IBM, the Linux Foundation and Microsoft to support Unified Patents’ Open Source Zone adds another key patent non-aggression initiative to our efforts.”

As part of the partnership, the companies will support Unified Patents’ Open Source Zone and provide an annual subscription. According to OIN, this should expand patent non-aggression activities and deter PAEs from targeting Linux and OSS technologies. Unified Patents is an international membership organization with a mission to improve patent quality and deter invalid patent assertions. The organization works to fight against invalid patents, never pays non-practicing entities (NPE) and deters future NPE activities through monitoring, analytics, and USPTO challenges. 

“Linux and open source technologies have become the backbone of modern computing and the systems we all rely upon,” said Jim Zemlin, Executive Director at the Linux Foundation. “We see significant value in partnering with OIN, IBM and Microsoft to support Unified Patent’s new Open Source Zone, deterring the activities of patent trolls working against the communities we all depend on.”

Mon, 18 Nov 2019 10:00:00 -0600 en-US text/html https://sdtimes.com/os/oin-ibm-microsoft-and-the-linux-foundation-team-up-against-open-source-patent-trolls/
Calgary Health Foundation appoints Sarah Kennedy as Interim Board Chair

Sarah Kennedy

Interim Board Chair, Calgary Health Foundation

Calgary, Alberta, Canada, Jan. 03, 2024 (GLOBE NEWSWIRE) -- Calgary Health Foundation Board Vice Chair Sarah Kennedy has been appointed as Interim Board Chair. Sarah has been a dedicated member of the Board for 11 years, providing thoughtful leadership as Vice Chair over the past four years.

“We are confident Sarah will continue to provide impactful leadership to our Board and organization in this new capacity. Her business acumen and commitment to the values and mission of Calgary Health Foundation have ensured significant achievements throughout her tenure, including the incredibly successful Newborns Need campaign. As we welcome Sarah, we would like to express our gratitude to Sandy Edmonstone for his strategic leadership as our Board Chair for the past four years and throughout his 14 years on our Board. Sandy will continue to make significant contributions to the health care space through his new appointment as AHS Board Vice Chair.” Murray Sigler, Calgary Health Foundation President & CEO.

Sarah is a respected leader in the business community and is presently a Lead Client Partner in the Energy and Industrial segment with IBM Consulting. Sarah’s involvement with the Calgary Health Foundation over more than 11 years has spanned her previous role as Vice Chair, as well as chairing the South Health Campus Fund Development Council for five years, where her team oversaw the successful fundraising campaign to build out of the Pediatric Emergency Pod and Care-by-Parent rooms. Sarah also played a critical role as part of the Cabinet for the Newborns Need campaign, which raised $65M to support families across southern Alberta.

In 2022, Sarah received the Queen’s Platinum Jubilee Medal from the AB Government in recognition of her many years of volunteer leadership. Sarah is also an advocate of increasing female participation in the areas of science, math, technology, and engineering as a former board member of the Calgary Chapter of Women in Communications and Technology.

“I’m very excited to be taking on the role of Interim Board Chair for Calgary Health Foundation. During my tenure with the Board, I have seen the incredible impact of this organization, and I am thrilled to move that work forward. Working with Calgary Health Foundation Board and staff, we will expand our reach and impact, inspiring and connecting more donors with giving opportunities that will lead to extraordinary health programs and outcomes.” - Sarah Kennedy

Calgary Health Foundation is a philanthropic organization uniting our donors, four hospitals, care providers, and community partners with the ambitious aim of revolutionizing health outcomes. Through deep cooperation, unrelenting persistence and a sharp focus on care, wellness, and research, we are unyielding in our efforts to ensure Calgarians receive the most progressive care in the world — because our loved ones and yours deserve nothing less. calgaryhealthfoundation.ca

Attachment

CONTACT: Shannon MacMillian Director, Communications | Calgary Health Foundation 403.472.9573 shannon.macmillan@calgaryhealthfoundation.ca
Wed, 03 Jan 2024 03:38:00 -0600 en-US text/html https://finance.yahoo.com/news/calgary-health-foundation-appoints-sarah-173800870.html




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